Template:Japanesestudy
Japanese study
The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines https://www.biorxiv.org/content/10.1101/2021.08.22.457114v1.full.pdf
This Japanese study published August 22, 2021 suggests that they think they need to "develop vaccines that protect against such complete breakthrough variants." which they are seeing.
Many of the top scientist do not believe that pharmaceutical industry will be able to safely produce a vaccine nor boosters for years if ever that do not produce the dangers of breakthrough resistance and mutation among the fully vaccinated demonstrated in the Japanese study published August 22, 2021, The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines.
An Oxford Clinical Research Group also published a preprint paper in the Lancet August 10, 2021 of a study which showed that fully vaccinated healthworkers carry 251 times the viral load of the COVID-19 in their nostrils compared to the unvaccinated
According to an article by Dr Peter McCullough, "While moderating the symptoms of infection, the jab allows vaccinated individuals to carry unusually high viral loads without becoming ill at first, potentially transforming them into presymptomatic superspreaders."
This means the danger is not from the unvaccinated individuals but from the vaccinated.
"This is consistent with the observations in the U.S. from Farinholt and colleagues, and congruent with comments by the director of the Centers for Disease Control and Prevention conceding COVID-19 vaccines have failed to stop transmission of SARS-CoV-2."
So, this would mean that any push to vaccinate people already immune or with sound health with no morbidities that puts them at risk what be the opposite of a sound health authority policy.
We also know from the The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines study that the larger pool of vccinated people the more mutations and varients may occur.
Nations following the real science are already reversing the positions that are creating the "breakthrough resistance" and mutation among the fully vaccinated. Mass innoculation is producing the danger of mutations of a "super resistant virus" among people who have become "super spreaders".
Iceland who is one of the top vaccinated nations is saying the only way to herd immunity is natural immunity because of so many "breakthroughs". https://fb.watch/7BNEfLLlZc/
Denmark has also abolished all Corona measures [1] in favor of natural immunity and lawyers warn business against pressuring employees to get vaccinated. https://www.bitchute.com/video/1jgm3KuWNWCq/Every health authority needs to follow the science and stop the unwarranted push to vaccinate the least vulnerable members of their society or military.
We can see on page 2 of the The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines, "Although Pfizer-BioNTech BNT162b2-immune sera neutralized the Delta variant, when four common mutations were introduced into the receptor binding domain (RBD) of the Delta variant (Delta 4+), some BNT162b2-immune sera lost neutralizing activity and enhanced the infectivity"
The epitopes that cause ADE are already present in the Delta strain, they're located in the NTD region. Most of the neutralizing antibodies against the NTD no longer work against Delta. The authors of this study warn that it takes just four mutations, mutations that are already quite common, to negate the neutralizing antibodies against the RBD.
We see that "The high frequency of reduced or enhanced recognition by anti-NTD antibodies against the Delta variant suggests that the antigenicity of the NTD has been greatly affected by mutations in the NTD." See on page 3.
The reason we see that The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines is because "The Delta variant has multiple mutations in the NTD: T19R, G142D, E156G, F157del and R158del." See on page 7.
"The Delta variant is highly contagious and breakthrough infection to fully vaccinated individuals" and the scientific study goes on to state that this is " suggesting that neutralizing antibodies in fully vaccinated individuals are not sufficient to protect against infection by the Delta variant." See on page 7.
Some see this as ADE being already a reality among fully vaccinated individuals. Because some antibodies still work sever problems are less visible. The more people who are vaccinated the more new variants will emerge which makes it possible for a super virus to emerge among the fully vaccinated individuals.
They also mention in passing that the four mutations they mention are just one possible route they studied that lead to complete vaccine resistance and antibody dependent enhancement. They warned that there could very well be other viable routes that would have the same effect.
The study mentions enhancing around 90 times.
"Enhancing antibodies increase the infectivity of SARS-CoV-2 by inducing the open form of the RBD (Liu et al., 2021b). As described above, the recognition by most of the enhancing antibodies was well conserved in the Delta variant (Figure 1A). When the effect of the enhancing antibodies was analyzed, the infectivity enhancement of the Delta pseudovirus by some of the enhancing antibodies was more than that of the wild-type pseudovirus (Figure 1D). These data suggested that the Delta variant completely escaped from anti-NTD neutralizing antibodies while maintaining functional enhancing antibody epitopes." Page 4.
And they also state on page 5 "When the effect of the enhancing antibodies was analyzed, the infectivity enhancement of the Delta pseudovirus by some of the enhancing antibodies was more than that of the wild-type pseudovirus".
As we have seen earlier Real scientists have known and explained there are "Two Different Antibody-Dependent Enhancement (ADE) Risks for SARS-CoV-2 Antibodies". If we understand that "Plasma therapy is a type of treatment in which the blood plasma of one person who has been ill with an infection and has recovered, is used to treat another individual whom has become ill with the same infection" then we may also understand that the ADE produced by plasma therapy has nothing to do with the ADE produced by an mRNA nano-particle intramuscular injection with PEG to produce replication.
The Real scientists' Summary concludes, "Given past data on multiple SARS-CoV-1 and MERS-CoV vaccine efforts have failed due to ADE in animal models (75, 81), it is reasonable to hypothesize a similar ADE risk for SARS-CoV-2 antibodies and vaccines. ADE risks may be associated with antibody level (which can wane over time after vaccination) and also if the antibodies are derived from prior exposures to other coronaviruses."
The larger the body of vaccinated people the greater potential for an immune virus that is highly infections which is gain of function but the process of Antibody enhancement will continue. These forced vaccination mandates and coercion appears to be a biological recipe for a true pandemic of ADE on steroids in the making for the fully vaccinated.
- ↑ Denmark abolishes all Corona measures. Danish parliament recently decided in Copenhagen that all Corona measures should be ended from October 1. There will therefore no longer be a mask requirement and the test regime will be abolished. The Danes will then no longer have to provide evidence of whether they are vaccinated or unvaccinated, or whether they have tested positive or negative.